Local anaesthetic sprays and pneumonia after gastroscopy.

Cardiac Arrest after Local Anaesthetic Toxicity in a Paediatric Patient

We report a case of a paediatric patient undergoing urological procedure in which a possible inadvertent intravascular or intraosseous injection of bupivacaine with adrenaline in usual doses caused subsequent cardiac arrest, completely reversed after administration of 20% intravenous lipid emulsion. Early diagnosis of local anaesthetics toxicity and adequate cardiovascular resuscitation manoeuv...

Late Local Anaesthetic Toxicity After Infraclavicular Block Procedure.

Local anaesthetic (LA) toxicity is the most fatal complication of peripheral nerve block techniques. Accidental intravascular application or use of doses above the safety range are the most common cause of toxicity. Bupivacaine is a long-acting LA frequently used for long procedures or those associated with significant post-procedural pain. Fatal central nervous system and cardiovascular system...

The toxic impact of local anaesthetics in menopausal women: causes, prevention and treatment after local anaesthetic overdose. Local anaesthetic systemic toxicity syndrome

Gynaecologists often use local anaesthetics in their medical practice. Some concomitant diseases during the menopausal period may cause problems during the qualification of postmenopausal women for general anaesthesia in gynaecological surgery. Many authors suggest the application of local analgesia for particular kinds of gynaecological surgery procedures performed on postmenopausal women, tak...

Developments in local anaesthetic drugs.

Most of the recent developments in local anaesthetics have been a direct consequence of the recognition, 20 yr ago, of the acute, life-threatening cardiotoxicity of bupivacaine. All local anaesthetics produce a dose dependent delay in the transmission of impulses through the cardiac conduction system by their action on the cardiac sodium and potassium channels. However, overt cardiotoxicity usu...

Local Anesthetic Lidocaine for Gastroscopy Induces Diffuse Alveolar Hemorrhage